Introduction: The life quality of patients with epileptic seizures is highly affected by cognitive deficits. Low Frequency Stimulation (LFS) is a novel approach for the treatment of pharmacoresistant epilepsy. The main goal of this research is investigating the possible effect of LFS on seizure-induced cognitive dysfunction.  Methods: To this end, the kindled animal were prepared via CA1 ...

Multiple Sclerosis (MS) is a disease of the central nervous system affecting millions of people worldwide. In addition to the disabling physical symptoms of MS, roughly 65% of individuals with MS also experience significant cognitive dysfunction, especially in the domains of learning/memory, processing speed (PS) and working memory (WM). The purpose of this review is to examine major topics in ...

Some patients with disorders affecting the hippocampus have relatively intact memory, but the mechanisms underlying this preservation of function are still debated. In particular, it is unclear whether preserved memory is attributable to significant residual function of unaffected hippocampus or to functional brain reorganization. Here, we investigated brain activation during an associative sho...

The study compared the prevalence of depression, memory dysfunction, and the influence of depression on memory in two contrasting age-groups of women: young--the mean age of approximately 23 years (35 subjects) and old--the mean age of approximately 70 years (44 subjects). The study population samples were subdivided into depressive and nondepressive groups, according to the presence and absenc...