In his recent book, Palliative Care: The 400-Year Quest for a Good Death, [1] Harold Vanderpool traces the emergence of medical palliation to a proclamation by Sir Francis Bacon in 1605 challenging physicians to offer and continually improve palliative medical care and treatment for dying persons. Florence Nightingale also contributed significantly to the evolution of what we call palliative ca...

Suggestive Synergy Between Genetic Variants in TF and HFE as Risk Factors for Alzheimer’s Disease J.S.K. Kauwe, S. Bertelsen, K. Mayo, C. Cruchaga, R. Abraham, P. Hollingworth, D. Harold, M.J. Owen, J. Williams, S. Lovestone, J.C. Morris, A.M. Goate* and the Alzheimer’s Disease Neuroimaging Initiative Department of Psychiatry & Neurology, Washington University School of Medicine, St. Louis, Mis...

Correspondence: Professor Dr med. Thomas Schläpfer, Department of Psychiatry, University of Bonn, Sigmund-Freud-Str. 25, 53105 Bonn, Germany. Tel. +49 228 287 15715; Fax: +49 228 287 15025. E-mail: [email protected] 1Task Force Members: Thomas E. Schlaepfer (chair), Mark S. George (co-chair), Helen Mayberg (co-chair), Frank Padberg (secretary). Members: Chittaranjan Andrade (India), Andreas Con...

Many philosophers think of Bayesianism as a theory of practical rationality. This is not at all surprising given that the view’s most striking successes have come in decision theory. Ramsey (1931), Savage (1972), and De Finetti (1964) showed how to interpret subjective degrees of belief in terms of betting behavior, and how to derive the central probabilistic requirement of coherence from refle...

FROM Niccolo Machiavelli and David Hume to E. H. Carr and Hans Morgenthau, power has been an important (some would say too important) variable in international political theorizing. Although some may regard power analysis as old-fashioned and outdated, recent refinements in social science thinking about power suggest the possibility of revitalizing this approach to understanding international r...

I. Effect of Fluoroacetate on the Conversion of Isotopic Acetate to Carbon Dioxide by the Mouse. Nathan Lifson and Joyce A. Swanson 1 11. N-Allylnormorphine: Effects of Single Doses and Precipitation of Acute “Abstinence Syndromes” During Addiction to Morphine, Methadone or Heroin in Man (Post-Addicts). Abraham Wikier, Havelock F. Fraser and Harris Isbell 8 III. Heparin-Like Anticoagulant Actio...