Adeno-associated virus serotype 4 (AAV4) and AAV5 have different tropisms compared to AAV2 and to each other. We recently reported that alpha 2--3 sialic acid is required for AAV5 binding and transduction. In this study, we characterized AAV4 binding and transduction and found it also binds sialic acid, but the specificity is significantly different from AAV5. AAV4 can hemagglutinate red blood ...

The nonlethal procedure of incubation in EDTA solution makes the peripheral regions of ascites sarcoma 37 cells more easily deformable, as reflected in measurements of the decreased amount of negative pressure required to suck out standard hemispherical bulges from the cells into micropipettes. The facilitation of deformability was abolished after reincubation of cells in calcium-containing sal...

The composition of the phospholipids and of the total phospholipid fatty acids was determined in the plasma of 10 normal subjects. In addition the fatty acid composition of the plasma phosphatidyl ethanolamine, phosphatidyl serine, lecithin, sphingomyelin, and lysolecithin of 6 of the subjects was measured. A wide array of fatty acids was found in the plasma total phospholipid similar to that f...

in present investigation the biological leaching of aluminum by isolated fungi from red mud, the main waste product of the alkaline extraction of al from bauxite was studied. biological leaching experiments were carried out using indigenous, date and orange specimen fungi, aspergillus niger, penicillium simplicissimum notatum. savored dextrose chloramphenicol agar (sda) was used as medium for t...

Folic acid deficiency is very common in elderly patients who have a mean red cell volume greater than 94 fl. Eighteen out of 40 elderly patients with red cell macrocytosis who initially had normal red cell folate and serum B12 levels subsequently developed folic acid deficiency.

Absorption: With the original technique (1) the horse serum decomplemented by heating to 56 0 C. and then absorbed against cells and pooled serum of the species to be treated; tion was done first to avoid hemolysis of the added red cedure had two flaws. First, the use of serum (rather than p.,,"~ ... aJ ICtJ,:'lgror absorption precluded the removal of antifibrinogen and bocyte antibodies. Secon...

In present investigation the biological leaching of aluminum by isolated fungi from red mud, the main waste product of the alkaline extraction of Al from bauxite was studied. Biological leaching experiments were carried out using indigenous, date and orange specimen fungi, Aspergillus Niger, Penicillium simplicissimum notatum. Savored Dextrose chloramphenicol Agar (SDA) wa...