One of the main objectives of our current work is the development of new somatostatin analogs that would retain the general characteristics of [Tyr(3)]octreotate (Tate) while showing potential for clinical application. In this respect, study of their interaction with the sst(2) is crucial in providing preliminary structure-activity relationships data. In the present work we report on the synthe...

this study aims to evaluate effects of two downscaling methods; change-factor and statistical downscaling on therunoff of the azam-harat river located at yazd province (with an arid climate) of iran, under the a2 emission scenariofor the period of 2010-2039. for this purpose, cgcm3-ar4 model; a rainfall-runoff conceptual model, ihacres; twodownscaling models, change factor and lars-wg were appl...

The climate risk zoning was carried out for cowpea cultivated in northeastern Amazonia, Pará state, Brazil. Système d’Analyse Régionale des Risques Agroclimatologiques (SARRA) crop model used and calibrated from data obtained field experiments conducted between 2013 2016 Castanhal, state of Pará. Low areas were defined as those with water requirement satisfaction index (WRSI) greater than or eq...

The wide ranging potential impacts of climate change on sustainable development and vice versa, suggest that the linkages between these two topics need to be critically analysed. Such an analysis was attempted in the IPCC third assessment report (TAR), and while some progress was made, the work was incomplete. This paper summarizes key lessons from the TAR and relevant post-TAR findings, as a s...

We couple a species range limit hypothesis with the output of an ensemble of general circulation models to project the poleward range limit of gray snapper. Using laboratory-derived thermal limits and statistical downscaling from IPCC AR4 general circulation models, we project that gray snapper will shift northwards; the magnitude of this shift is dependent on the magnitude of climate change. W...

Article 2 of the United Nations Framework Convention on Climate Change [United Nations (1992) http://unfccc.int/resource/docs/convkp/conveng.pdf. Accessed February 9, 2009] commits signatory nations to stabilizing greenhouse gas concentrations in the atmosphere at a level that "would prevent dangerous anthropogenic interference (DAI) with the climate system." In an effort to provide some insigh...

[1] The radiative effects from increased concentrations of well-mixed greenhouse gases (WMGHGs) represent the most significant and best understood anthropogenic forcing of the climate system. The most comprehensive tools for simulating past and future climates influenced by WMGHGs are fully coupled atmosphere-ocean general circulation models (AOGCMs). Because of the importance of WMGHGs as forc...

North Sea. Holt et al. (2014, reference in the manuscript) found the North Sea less sensitive to production changes and projected less consequences of climate change for the North Sea compared to the global ocean, whereby Gröger et al (2013, reference in the manuscript) found the opposite, a more sensitive North Sea production to climate change. The question of regional consequences of climate ...