BACKGROUND Double-blind placebo-controlled food challenge, DBPCFC, the gold standard for diagnosing food allergy, is time-consuming and potentially dangerous. A basophil allergen threshold sensitivity test, CD-sens, has shown promising results as a diagnostic tool in food allergy. OBJECTIVES To evaluate the reproducibility of oral peanut challenge and compare the outcome to CD-sens in peanut-...

Background and Objectives: Spiritual health has a positive effect on the organizational behavior of healthcare personnel with patients as well as organizational productivity. Accordingly, the present study aimed to investigate the relationship between spiritual health and job performance of operating room personnel working in the academic hospitals of Qom, Iran, during 2017-2018. Methods: This...

SENS (Strategies for Engineered Negligible Senescence) is a panel of proposed interventions in mammalian aging that I have suggested may be sufficiently feasible, comprehensive, and amenable to subsequent incremental refinement that it could prevent death from old age (at any age) within a time frame of decades, leading to four-digit lifespans of many people alive today. This extreme conclusion...

Current models for predicting outcomes are limited by biases inherent in a priori hypothesis generation. Knowledge discovery algorithms generate models directly from databases, minimizing such limitations. Our objective was to generate a mortality model from a PICU database utilizing knowledge discovery techniques. The database contained 5067 records with 192 clinically relevant variables. It w...

Objectives: We performed a systematic review to investigate the quality of diagnostic hospital discharge data (DHDD) in order to gain insight in the usefulness of these data for medical practice assessment. We investigated the methods used to evaluate data quality, factors that determine data quality and its consequences for medical practice assessment. Methods: We selected studies in which bot...