نتایج جستجو برای: specific activation strategy
تعداد نتایج: 1692049 فیلتر نتایج به سال:
Abstract NLRP3 inflammasome plays an important role in innate immune system through recognizing pathogenic microorganisms and danger-associated molecules. Deubiquitination of has been shown to be essential for its activation, yet the functions Ubc13, K63-linked specific ubiquitin-conjugating enzyme E2, activation are not known. In this study, we found that mouse macrophages, Ubc13 knockdown or ...
apoptosis or programmed cell death is a gene regulated phenomenon which is important in both physiological and pathological conditions. it is characterized by distinct morphological features including chromatin condensation, cell and nuclear shrinkage, membrane blebbing and oligonucleosomal dna fragmentation. although, two major apoptotic pathways including 1) the death receptor (extrinsic) and...
BACKGROUND Considerable evidence suggests that performance across a variety of cognitive tasks is effectively supported by the use of verbal and nonverbal strategies. Studies exploring the usefulness of such strategies in children with specific language impairment (SLI) are scarce and report inconsistent findings. AIMS To examine the effects of induced labelling and auditory cues on the perfo...
Introduction: One of the topics in health psychology is the response of individuals to the physical symptoms of the disease. Cognitive emotion regulation strategies deal with adaptive emotion. Method: The study method is correlational. The population includes students aged 18 to 35 years from Bu Ali Sina University and Payame Noor University of Hamadan. To conduct research, 399 students were se...
Nuclear receptors undergo ligand-dependent conformational changes that are required for corepressor-coactivator exchange, but whether there is an actual requirement for specific epigenetic landmarks to impose ligand dependency for gene activation remains unknown. Here we report an unexpected and general strategy that is based on the requirement for specific cohorts of inhibitory histone methylt...
Background and Objectives: Coronavirus 2019 (Covid-19) has become a global disease that can affect various organs of the human body. Kidney disorders are the most common disorders in patients with Covid-19. Kidney involvement manifests as proteinuria and acute kidney injury (AKI). This virus can cause acute tubular necrosis, protein leakage in the Bowman's capsule, glomerulopathy, and mitochond...
hedging is a multi-purpose rhetorical strategy which is usually used in scientific arguments to secure ratification of claims, reduce the risk of negation, avoid conflict, manage disagreement and leave room for the audience to assess presented information. hedges are frequently used in research articles to mitigate the findings of research endeavors. the present research aims to investigate the...
Apoptosis or programmed cell death is a gene regulated phenomenon which is important in both physiological and pathological conditions. It is characterized by distinct morphological features including chromatin condensation, cell and nuclear shrinkage, membrane blebbing and oligonucleosomal DNA fragmentation. Although, two major apoptotic pathways including 1) the death receptor (extrinsic) and...
Introduction: Inflammatory processes has an important role in the Multiple Sclerosis (MS)’s pathophysiology. Therefore, hampering the inflammatory factors could be an effective strategy in MS treatment. Piperine (the main alkaloid of black piper) has immunomodulatory and anti-inflammatory properties. In this study the pre-treatment effects of piperine on the gene expression level of inflammator...
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