نتایج جستجو برای: therapeutic response
تعداد نتایج: 1276893 فیلتر نتایج به سال:
Background: Chronic graft versus host disease (cGVHD) is a major cutaneous complication of bone marrow transplantation (BMT). Although milder forms of this process may be associated with a lower incidence of tumor recurrences, it is mandatory to develop a more efficient and less harmful therapeutic approach.Methods: This case-series study enrolled 7 patients diagnosed with chronic mucocutaneous...
Ovarian Hyperstimulation Syndrome (OHSS) is a rare complication of super ovulation and in vitro fertilization (IVF). Although our understanding of its pathophysiology is incomplete, induction of development of multiple follicles, perturbation of the renin angiotensin system and exposure to luteinizing hormone (LH) or human chorionic gonadotropin (hCG) are essential contributing factors to its d...
The colorectal cancer (CRC) subtyping consortium has unified six independent molecular classification systems, based on gene expression data, into a single consensus system with four distinct groups, known as the consensus molecular subtypes (CMS); clinical implications are discussed in this review based on articles relevant to the CMS of CRC indexed in PubMed as well as the authors’ own ...
Abstract Background and purpose: To determine the effect of intrasphincteric botulinum toxin injection to treat internal anal sphincter achalasia. Materials and methods: Twenty patients (11 boys, average age 4.95± 2.47 years) with definite diagnosis of internal anal sphincter achalasia received 20 units of botulinum toxin injection in 4 points of the internal anal sphincter (totally 80 unit...
این مطالعه به منظور بررسی الگوی مصرف و تجویز سفالسپورینهای نسل سوم در بیمارستان امام انجام شد. مطالعه به دو روش گذشته نگر retrospective بر روی پرونده 200 بیمار که از تاریخ فروردین 75 تا مهر 77 در بخشهای عفونی مردان و زنان، مرکز طبی کودکان، طبی 6، طبی 1 و 2 و icu بیمارستان امام بستری بودند انجام گرفت و قسمت حال نگرconcurrent بر روی 200 بیمار بستری در بخش عفونی مردان و زنان انجام شد. متغیرهای مور...
Vitiligo is a common idiopathic acquired cutaneous pigmentary disorder resulting in depigmented skin. A wide variety of therapeutic modalities have been employed for its treatment, but none of them are satisfactory, in this study we have tested the effect of 5- fluorouracil 5FU on 54 patients with documented vitiligo in Kerman city. The following treatments were performed on three selected v...
Traumatic brain injury (TBI) is a leading cause of death and disability worldwide and many survivors experience a wide range of neurological impairments after TBI. Following the initial mechanical injury at the moment of a TBI event, various cellular and molecular processes are activated as the secondary injury. Neuroinflammation is an important mechanism involved in the secondary injury of TBI...
Objective(s): Program death 1 (PD-1)/ program death-ligand 1 (PD-L1) pathways, as the main inhibitory checkpoints, induce immunosuppression in the tumor microenvironment (TME). Despite the importance of inhibitor checkpoint receptor (ICR) blockers, their outcomes have been limited by the low immune response rate and induced acquired resistance. Pre-existing tumor-speci...
The therapeutic efficacy of the combination of cyproheptadine and bromocriptine was studied in 15 patients with active acromegaly showing incomplete GH suppression in response to bromocriptine therapy alone. The mean basal plasma GH was 31.3±5.5 µg/L, and it decreased to 19.0±3.9 µg/L during the single bromocriptine therapy (10-20 mg for 2 to 21 months). When cyproheptadine (12 to 16 mg for 8 t...
Hepatitis C virus (HCV) infection has affected approximately 180 million people across the world. In most cases, HCV-infection remains chronic, which expose patients at high risk of cirrhosis and hepatocellular carcinoma. The rates of disease incidence and mortality diminish as a result of successful treatment of HCV infection. Until the recent years, despite the associated toxicities and l...
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