abstractin this study, a vendor-managed inventory model is developed for a single-vendor multiple-retailer single-warehouse (sv-mr-sv) supply chain problem based on the economic order quantity in which demands are stochastic and follow a uniform probability distribution. in order to reduce holding costs and to help balanced on-hand inventory cost between the vendor and the retailers, it is assu...

background: irreversible electroporation (ire) is a novel tumor ablation technique. ire is associated with high electrical fields and is often reported in conjunction with thermal damage caused by joule heating. for good response to surgery it is crucial to produce minimum thermal damage in both tumoral and healthy tissues named non-thermal irreversible electroporation(ntire). non-thermal irrev...

this work intends to deal with the optimal kinematic synthesis problem of tricept parallel manipulator. observing that cuboid workspaces are desirable for most machines, we use the concept of effective inscribed cuboid workspace, which reflects requirements on the workspace shape, volume and quality, simultaneously. the effectiveness of a workspace is characterized by the dexterity of the manip...

In this paper a hybrid algorithm based on exploration power of the Genetic algorithms and exploitation capability of Nelder Mead simplex is presented for global optimization of multi-variable functions. Some modifications are imposed on genetic algorithm to improve its capability and efficiency while being hybridized with Simplex method. Benchmark test examples of structural optimization with a...

t his paper presents a new feature selection approach for automatically extracting   ms lesions in 3d mr images. presented method is applicable to different types of ms lesions. in this method, t1, t2 and flair images are firstly preprocessed. in the next phase, effective features to extract ms lesions are selected by using a genetic algorithm. the fitness function of the genetic algorithm is t...

This paper addresses the multi-mode multi-skilled resource-constrained project scheduling problem. Activities of real world projects often require more than one skill to be accomplished. Besides, in many real-world situations, the resources are multi-skilled workforces. In presence of multi-skilled resources, it is required to determine the combination of workforces assigned to each activity. H...

this paper uses integrated data envelopment analysis (dea) models to rank all extreme and non-extreme efficient decision making units (dmus) and then applies integrated dea ranking method as a criterion to modify genetic algorithm (ga) for finding pareto optimal solutions of a multi objective programming (mop) problem. the researchers have used ranking method as a shortcut way to modify ga to d...

multiple traveling salesman problem (mtsp) is one of the most popular operation research problem and is known as combinatorial optimization problems. mtsp is an extension version of the famous and widely used problem named traveling salesman problem (tsp). because of its benefices in various domains, many researchers have tried to solve that, and many methods have proposed so far. mtsp is a np-...

Structural changes are critical for biological functions of proteins and describing conformational changes in large macromolecular complexes is a major challenge. To allow full studies of gradual conformational changes, we have recently developed Hybrid Electron Microscopy Normal Mode Analysis (HEMNMA) [1]. HEMNMA uses normal modes to elastically align electron microscopy (EM) images with a ref...