Adaptation of Saccharomyces cerevisiae cells to arsenic stress is mediated through the activation of arsenic detoxification machinery by the Yap8 transcription factor. Yap8 is targeted by the ubiquitin proteasome system for degradation under physiological conditions, yet it escapes proteolysis in arsenic-injured cells by amechanism that remains to be elucidated. Here, we show that Ufd2, an E4-U...

Arsenic-containing lipids (arsenolipids) are natural products present in fish and algae. Because these compounds occur in foods, there is considerable interest in their human toxicology. We report the synthesis and characterization of seven arsenic-containing lipids, including six natural products. The compounds comprise dimethylarsinyl groups attached to saturated long-chain hydrocarbons (thre...

Arsenic is considered as one of the most important environmental contaminant elements. Some plant species can grow in arsenic contaminated soils and they are able to reduce arsenic toxicity. In this study, a hydroponic experiment was conducted on Isatis cappadocica, a newly-discovered As hyperaccumulator. Accordingly, we conducted this experiment to compare the interaction of effect of arsenic ...

Arsenic, an important environmental contaminant, is present in the aquatic environment as a result of geogenic and anthropogenic processes (Gonzaliz et al., 2006; Singh and Banerjee, 2008) and it has been reported as one of the most alarming chemical (ATSDR, 2002). In the environment, arsenic is present in different forms and the toxicity depends upon its chemical form and oxidation states (Agu...

In the past several years, concern about the presence of arsenic (As) in apple juice has grown greatly due to its publicity in the popular media. Arsenic can enter apple juice either naturally through environmental uptake by the apple trees or anthropogenically through the use of pesticides and/or contamination during processing. Regardless of how it enters the juice, the presence of arsenic is...