background: evaluating the significance and the effects of plant-derived drugs on laboratory animal’s fertility was recognized. there was antioxidant activity reported from heracleum persicum (golpar).objective: current study aims to study the antioxidant effect of golpar extracts on sperm parameters and chromatin quality in mice.materials and methods: eighteen adult male mice were divided to 3...

Background: Acrylamid (AA) is found in carbohydraterich foods that are prepared at high temperatures, such as French fries and potato chips. The toxic effects of AA in male animals include degeneration of epithelial cells of seminiferous tubules, decreased number of sperm and elevation in abnormal spermatozoa. The aim of this study was to evaluate the detrimental effects of AA on sperm paramete...

varicocele is one of the most common causes of primary male infertility. pilea microphylla (pm) is being used as folk medicine. this study was aimed to investigate the effects of pm in a rat model of varicocele. a total of 30 male wistar rats were divided into control, sham, varicocele, accessory varicocele and pm-treated groups. after 10 weeks of varicocele induction, sperm parameters and chro...

Background Flow cytometry (FCM) has been extensively used to study mammalian sperm in the areas of clinical andrology and reproductive toxicology. FCM provides a powerful advantage over microscopy technique in terms of rapid accurate and reproducible technology for the quantification of various cell characteristics including chromatin status. During spermiogenesis histones are replaced by prota...

Background: Little is known about Giberellic acid, a plant growth regulator used in many countries, on sperm parameters; so this study was conducted to evaluate its effects on sperm parameters. Materials and Methods: A number of twenty seven adult rats were divided into three groups (n=9): control group (C), control-sham group (C-Sh) and treatment group (Tr). The C-Shgroupand the Tr group were ...

Background: Varicocele occurs in approximately 15% to 20% of the male population and it is the most common cause of poor semen parameters. It has been demonstrated that patients with varicocele have poor chromatin packing, DNA damage and nuclear anomalies than the healthy men. Therefore, the aim of this study was to evaluate sperm chromatin integrity and semen parameters in these patients after...

 Introducing a Guideline for Preparing an Article from a Thesis: A Continuing Education Article M. Rezaeian[1]     Received: 14/10/2020  Sent for Revision: 02/11/2020 Received Revised Manuscript: 08/11/2020 Accepted: 09/11/2020     The necessity of publishing articles from diverse levels of education has always been emphasized. This would help to increase the likelihood of the use of th...