نتایج جستجو برای: thiotcpa t group and thiotepa cetrorelix

تعداد نتایج: 17021395  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1996
G Halmos A V Schally J Pinski M Vadillo-Buenfil K Groot

Antagonists of luteinizing hormone-releasing hormone (LH-RH), unlike the LH-RH agonists, suppress gonadotropins and sex steroid secretion immediately after administration, without initial stimulatory effects. [Ac-D-Nal(2)1,D-Ph(4Cl)2,D-Pal(3)3,D-Cit6,D-Ala10]LH-R H (SB-75; Cetrorelix) is a modern, potent antagonistic analog of LH-RH. In this study, the binding characteristics of receptors for L...

Journal: :Cancer research 1995
H A Dirven E L Dictus N L Broeders B van Ommen P J van Bladeren

Nonenzymatic and glutathione S-transferase (GST) catalyzed glutathione (GSH) conjugation has been postulated as a mechanism by which alkylating cytostatic drugs can be inactivated intracellularly. In this study, we describe studies on the glutathione-dependent biotransformation of thiotepa (tris(1-aziridinyl)phosphine sulfide), a trifunctional alkylating agent. 31P NMR studies showed that thiot...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه مازندران - دانشکده علوم انسانی و اجتماعی 1390

teachers beliefs have usually been left unattended in the realm of educational research in iranian context. one of those beliefs which seems to impact teachers performance in the classroom is their sense of self-efficacy, which refers to teachers belief in their ability to enhance student achievement and in bringing about positive learning outcomes. the present study aimed to investigate the pr...

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد گرمسار - دانشکده ادبیات و زبانهای خارجی 1391

this study was an attempt to investigate the effect of teaching meta cognitive strategies on iranian intermediate efl students speaking proficiency. in this study the researcher has employed metacognitive strategies taken from brown (2000) to teach speaking strategies to number of participants. the participants were intermediate students of shokouh language institute; they were divided into an ...

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد گرمسار - پژوهشکده علوم انسانی و اجتماعی 1390

this study was an attempt to investigate and compare the effect of lexical inferencing and concept mapping on developing vocabulary retention of iranian language learners. sixty homogeneous students from different intact classes who were being taught as intermediate learners in sokhan english institute participated in this study. they were in different classes. a teacher made test as a pre-test...

Journal: :International journal of oncology 2009
Stefan Buchholz Stephan Seitz Andrew V Schally Jörg B Engel Ferenc G Rick Luca Szalontay Florian Hohla Awtar Krishan Andrea Papadia Timo Gaiser Gero Brockhoff Olaf Ortmann Klaus Diedrich Frank Köster

The aim of the present study was to evaluate the expression of receptors for luteinizing hormone-releasing hormone (LHRH) in human specimens of triple-negative breast cancers (TNBC). In addition, we used in vitro and in vivo models of TNBC to investigate if these receptors are suitable targets for the treatment with the LHRH antagonist cetrorelix. Receptors for LHRH were expressed in all tumor ...

Journal: :Human reproduction 2004
Jiann-Loung Hwang Kok-Min Seow Yu-Hung Lin Lee-Wen Huang Bih-Chwen Hsieh Yieh-Loong Tsai Gong-Jhe Wu Shih-Chia Huang Chin-Yu Chen Pei-Hsin Chen Chii-Ruey Tzeng

BACKGROUND Patients with polycystic ovary syndrome (PCOS) may need a longer period of pituitary downregulation to suppress the elevated serum LH and androgen levels effectively during IVF treatment using the GnRH agonist long protocol. We proposed a stimulation protocol incorporating Diane-35 and GnRH antagonist (Diane/cetrorelix protocol) and compared it with the GnRH agonist long protocol for...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه ولی عصر (عج) - رفسنجان - دانشکده ریاضی 1389

in this thesis, first the notion of weak mutual associativity (w.m.a.) and the necessary and sufficient condition for a $(l,gamma)$-associated hypersemigroup $(h, ast)$ derived from some family of $lesssim$-preordered semigroups to be a hypergroup, are given. second, by proving the fact that the concrete categories, semihypergroups and hypergroups have not free objects we will introduce t...

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد گرمسار - دانشکده ادبیات و علوم انسانی 1390

abstract the present study tried to investigate the effect of visual aids (films) on the development of the speech act of disagreement among iranian efl intermediate learners. to this end, the researcher selected 40 homogeneous intermediate learners based on their scores on oxford placement test. .the subjects then divided into control group and experimental group. both classes were tested by ...

Journal: :In vivo 2012
Chryssa Metallinou Frank Köster Klaus Diedrich Nikos Nikolettos Byron Asimakopoulos

BACKGROUND We investigated the effects of the gonadotropin-releasing hormone (GnRH) agonist triptorelin as well the GnRH antagonist cetrorelix those of on the viability and steroidogenesis in human granulosa luteinized (hGL) cell cultures. MATERIALS AND METHODS The hGL cells were obtained from 34 women undergoing ovarian stimulation for IVF treatment. The cells were cultured for 48 h with or ...

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