objective(s): erythropoietin (epo), is a 34kda glycoprotein hormone, which belongs to type 1 cytokine superfamily. epo involves in erythrocyte maturation through inhibition of apoptosis in erythroid cells. besides its main function, protective effects of epo in heart and brain tissues have been reported. epo has a critical role in development, growth, and homeostasis of brain. furthermore epo h...

Objective(s): The aim of this study is to investigate the renoprotective effect of erythropoietin (EPO) on hypovolemic shock and ischemia/reperfusion (IR) injury on kidneys as end-organs in an experimentally-created ruptured abdominal aortic aneurysm (rAAA) model.Materials and Methods: Thirty anesthetized Sprague-Dawley male rats were ra...

Objective(s): Erythropoietin (EPO), is a 34KDa glycoprotein hormone, which belongs to type 1 cytokine superfamily. EPO involves in erythrocyte maturation through inhibition of apoptosis in erythroid cells. Besides its main function, protective effects of EPO in heart and brain tissues have been reported. EPO has a critical role in development, growth, and homeostasis of brain. Furthermore EPO h...

Carbopol polymers are of acrylic acid and crosslinking agents; there is the prospect penetration linear macromolecules between mesh size crosslinked microgels for a certain period time. Interpolyelectrolyte complex (IPEC) samples polycations (Eudragit EPO—EPO) were obtained at different interpolyelectrolyte reaction (IPER) times (1, 3, 7 days). Confirmation IPEC structures was proved by FTIR mD...

One of the most common causes of mortality in acute kidney injury is brain dysfunction. Here we investigated the possible protective effect of erythropoietin (EPO) on cognitive impairments induced by bilateral renal ischemia (BRI). Eighty male Wistar rats were allocated into 8 groups: 1, 2) Sham+V (Vehicle), 3, 4) Sham+EPO, 5, 6) BRI+V, 7, 8) BRI+EPO. The groups followed by the reperfusion per...

background: erythropoietin (epo) is known as a regulating hormone for the production of red blood cells, called erythropoiesis. some studies have shown that epo exerts some non-hematopoietic protective effects on ischemia-reperfusion injuries in myocytes. using echocardiography, we evaluated the effect of epo infusion on reducing ischemia-reperfusion injuries and improvement of the cardiac func...

Background: Erythropoietin (EPO) is known as a regulating hormone for the production of red blood cells, called erythropoiesis. Some studies have shown that EPO exerts some non-hematopoietic protective effects on ischemia-reperfusion injuries in myocytes. Using echocardiography, we evaluated the effect of EPO infusion on reducing ischemia-reperfusion injuries and improvement of the cardiac func...