background: pre-eclampsia (pe) is one of the most important and life-threatening pregnancy disorders that affect at least 3-5% of all pregnancies. imbalance in helper t cell functions may play a role in predisposing to pe or severity of the disease. elevated frequencies of th17 cells in the peripheral blood of pe patients have been reported. several single nucleotide polymorphisms (snp) within ...

Objective(s): Sepsis can result in severe organ injury by provoking inflammatory cascades and oxidative stress. Several studies are currently underway to find a drug with anti-inflammatory effects to prevent mortality and morbidity during sepsis. The present study was undertaken to assess the effects of metformin on oxidative stress and antioxidant status in sepsis induced by the Cecal Ligation...

Objective(s): Nowadays, examining the toxicity of nanoparticles including the synthesized and functionalized iron nanoparticles using methods like green synthesis is highly considered, due to their increasing usage in various fields of medicine, biology, industrial, and pollution removal. Hence, in this study, the toxicity of the zero valent iron nanoparticles synthesized by plant-Myrtus commun...

stem cells are naïve or master cells. this means they can transform into special 200 cell types as needed by body, and each of these cells has just one function. stem cells are found in many parts of the human body, although some sources have richer concentrations than others. some excellent sources of stem cells, such as bone marrow, peripheral blood, cord blood, other tissue stem cells and hu...

aluminum phosphide (alp) as 3 g tablet is widely used in iran to protect stored food grains from pests. hyperglycemia following its ingestion has been already reported in the recent years but severe hypoglycemia is uncommon. here, we report a 19 year old male who attempted suicide with one tablet of alp and demonstrated severe hypoglycemia. despite restoration of blood glucose concentration to ...

Induced oxidative stress in diabetes mellitus (DM) plays a critical role in insulin resistance. Fork head-related transcription factor (FOXO) proteins are important transcriptional factors involved in oxidative stress and insulin resistance. Resveratrol (RSV) is a polyphenol with hypoglycemic and antioxidant properties. The aims of the present study were to examine the effects of RSV on FOXO ge...

objective: to evaluate the effect of fibrin perihepatic packing on controlling liver hemorrhage and liver wound healing. methods: in this animal experimental study, 20 adult male sprague dawley rats, weighing 200-220 g, were included. stab wound injury was created by number 15 scalpel, so that bilateral liver capsules and liver tissue were cut, and acute bleeding was accrued. the animals were d...